American journal of surgery · 2026
Trends and disparities in mortality due to small intestinal malignancies in the United States: A nationwide analysis from 1999 to 2023.
СтатьяНазвание и аннотация: Перевод в очереди
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Du Fan, Pan Wenkai, Huang Zhongke
Аннотация
BACKGROUND: Small intestinal malignancies contribute increasingly to cancer mortality. This study evaluates US mortality trends and disparities from 1999 to 2023 to address limited data on long-term patterns.
METHODS: Mortality data for adults ≥25 years were obtained from CDC WONDER. Joinpoint regression was used to estimate temporal trends in age-adjusted mortality rates (AAMRs) and calculate annual percent changes (APCs).
RESULTS: The overall AAMR increased (AAPC = 0.91%), accelerating significantly after 2010 (APC = 2.03%). Crude rates rose continuously in adults ≥85 years (APC = 2.07%) but declined in the 35-44 group. Women experienced a steeper mortality acceleration after 2013 than men. Non-Hispanic Blacks sustained the highest steady mortality, while Hispanics exhibited a rapid rise after 2015 (APC = 4.70%). Geographically, the South showed marked acceleration after 2012.
CONCLUSION: Mortality increased significantly with accelerating trends and marked sociodemographic disparities. These findings highlight the urgent need for targeted prevention and equitable access to care.
METHODS: Mortality data for adults ≥25 years were obtained from CDC WONDER. Joinpoint regression was used to estimate temporal trends in age-adjusted mortality rates (AAMRs) and calculate annual percent changes (APCs).
RESULTS: The overall AAMR increased (AAPC = 0.91%), accelerating significantly after 2010 (APC = 2.03%). Crude rates rose continuously in adults ≥85 years (APC = 2.07%) but declined in the 35-44 group. Women experienced a steeper mortality acceleration after 2013 than men. Non-Hispanic Blacks sustained the highest steady mortality, while Hispanics exhibited a rapid rise after 2015 (APC = 4.70%). Geographically, the South showed marked acceleration after 2012.
CONCLUSION: Mortality increased significantly with accelerating trends and marked sociodemographic disparities. These findings highlight the urgent need for targeted prevention and equitable access to care.