[The effect of primary tumor localization on radiotherapy for supraglottic and glottic cancer].

In the group of 544 patients with squamous cell cancer of supraglottic and glottic larynx the effect of primary tumour localisation on the response to radiotherapy was analysed. There were 156 patients with glottic cancer T1-T3 N0-N2 and 388 patients with supraglottic cancer with T1-T4 N0-N3. The most common site of extralaryngeal involvement was piriform fossa. All patients were treated with the use of external megavoltage beam. The total dose was in range 59-80 Gy. The 5-year actuarial disease-free survival was 36% for supraglottic cancer and 63% for glottic cancer. Primary tumour localisation in glottis correlates with more favourable prognosis than that in supraglottic. Extension from supraglottis to glottis worsened the prognosis more than that in opposite direction. For extralaryngeal involvement the most favourable prognosis was the infiltration of lingual-epiglottidean fossa and the worst one for the base of tongue involvement.