Clinical nephrology · 2024
Gastric Burkitt's monomorphic post-transplant lymphoproliferative disorder after kidney transplantation: A case report.
Клинический случайСтатьяНазвание и аннотация: Перевод в очереди
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Yoshimura Yusuke, Suwabe Tatsuya, Fujiki Arisa, Kaji Daisuke, Asano-Mori Yuki, Oba Yuki, Mizuno Hiroki, Yamanouchi Masayuki, Tanaka Kiho, Hasegawa Eiko, Miki Katsuyuki, Yokoyama Takayoshi, Namamura Yuki, Ishii Yasuo, Yamashita Satoshi, Kono Kei, Kinowaki Keiichi, Takazawa Yutaka, Sawa Naoki, Ubara Yoshifumi
Аннотация
We report on a 53-year-old Japanese man diagnosed with gastric Burkitt's monomorphic post-transplant lymphoproliferative disorder (B-PTLD) after endoscopy for gastric discomfort 28 months after the patient underwent renal transplantation in Ethiopia. Serum Epstein-Barr virus (EBV) tests were negative before transplantation, but the tumor cells collected from a gastric biopsy showed positive EBV-encoded small RNAs (EBER) at B-PTLD onset. Intensive treatment started with R(rituximab)-CHOP therapy and continued with DA-EPOCH-R therapy has been effective, and relapse has not yet occurred. Burkitt lymphoma has a poor prognosis, but B-PTLD may be effectively treated with high-dose chemotherapy. This is a rare case of gastric B-PTLD in a Japanese patient.