Autologous simple limbal stem cell transplantation with conjunctival autograft in chronic unilateral total LSCD with severe symblepharon due to severe alkali burn.

This report details the case of a middle-aged man with chronic unilateral total limbal stem cell deficiency with severe symblepharon in his left eye with upper lid mechanical ptosis, restricted ocular movements and visual acuity limited to counting fingers at 2 feet. 9 months prior to his first visit, he sustained an accidental unilateral alkali injury to the left eye. He underwent autologous simple limbal epithelial transplantation combined with conjunctival autograft in the left eye. Complete ocular surface epithelialisation was achieved within 24 days post surgery. After 24 months of follow-up, the patient exhibited a stable ocular surface, normal palpebral fissure and full range of eye movements, with a best-corrected visual acuity of 6/12p in the left eye.