Lobular endocervical glandular hyperplasia: Two case report and literature review.

RATIONALE: Lobular endocervical glandular hyperplasia is a rare proliferative lesion of the endocervical glands with an unclear pathogenesis. The condition lacks specific clinical manifestations and signs and often leading to clinical underdiagnosis and misdiagnosis.

PATIENT CONCERNS: A 27-year-old female patient presented with a history of abnormal vaginal bleeding over the previous 3 months. An ultrasound examination revealed the presence of a cystic solid structure in the posterior wall of the cervix.The second patient is a 25-year-old woman who has undergone 3 cervical cystectomies over the past 9 years due to recurrent cervical cysts. It is regrettable to report that the cyst has now recurred.

DIAGNOSES: Lobular endocervical glandular hyperplasia.

INTERVENTIONS: In consideration of the fertility needs of both patients, the gynecologists conducted a comprehensive imaging evaluation and detailed preoperative discussion, and performed ultrasound-guided hysteroscopic excision of cervical lesions and transvaginal excision of cervical lesions.

OUTCOMES: Following treatment, the 2 patients exhibited a complete resolution of their clinical symptoms. Subsequent follow-up examinations demonstrated that both patients were exhibiting favorable outcomes.

LESSONS: The objective of this study is to present 2 cases of lobular endocervical glandular hyperplasia in order to facilitate a greater understanding of this rare disease among gynecologists. Furthermore, this study will describe the potential use of ultrasound-guided hysteroscopic excision of cervical lesions and transvaginal hysteroscopic excision of cervical lesions as a treatment modality for lobular endocervical glandular hyperplasia patients with fertility needs.