Primary Non-Hodgkin Lymphoma of the Liver and Gallbladder Diagnosed by Laparoscopic Segment 8 Subsegmentectomy and Cholecystectomy: A Rare Case Report.

A 71-year-old Japanese woman presented to our hospital to consult for a gallbladder polyp detected on a routine ultrasound in 2024. We found a sized-up gallbladder polyp and a liver tumor. She underwent laparoscopic segment 8 subsegmentectomy and cholecystectomy for suspected malignancy. Pathology revealed aggressive follicular lymphoma of the liver and gallbladder. Immunohistochemical staining was positive for CD10, CD20, CD23, CD79a, BCL-2, and BCL-6, and negative for CD3, CD5, and cyclin-D1. Primary hepatic lymphoma and gallbladder polyp are accidental, and diagnosis is difficult without tissue biopsy or specimens. Laparoscopic hepatectomy facilitates accurate diagnosis and early postoperative recovery, enabling rapid chemotherapy administration.