Leukemia & lymphoma · 2024
Treatment outcome, toxicity, and quality of life of patients with bronchus-associated lymphoid tissue lymphoma.
СтатьяНазвание и аннотация: Перевод в очереди
Обработка статьи · этапы, ошибки и управление
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Gao Lin-Rui, Wang Xinyue, Wu Yunpeng, Feng Xiao-Li, Rao Wei, Liu Xin, Song Yong-Wen, Fang Hui, Chen Bo, Jin Jing, Liu Yue-Ping, Jing Hao, Tang Yuan, Lu Ning-Ning, Li Ning, Zhang Wen-Wen, Zhai Yirui, Wang Shu-Lian, Qi Shu-Nan, Li Ye-Xiong
Аннотация
The disease failure patterns and optimal treatment of bronchus-associated lymphoid tissue (BALT) lymphoma are unknown. This retrospective study involved 71 patients with primary BALT lymphoma who had received radiotherapy (RT), surgery, immunochemotherapy (IC), or observation. The median follow-up time was 66 months. The 5-year overall survival and lymphoma-specific survival were 91.2% and 96.1%, respectively, and were not significantly different among treatments. The 5-year cumulative incidence of overall failure for RT, surgery, IC, and observation was 0%, 9.7% (p = .160), 30.8% (p = .017), and 31.3% (p = .039). There was no grade ≥3 toxicity in RT group according to the CTCAE 5.0 reporting system. Quality of life (QoL) was at similarly good levels among the treatment groups. BALT lymphoma had a favorable prognosis but persistent risk of relapse after IC or observation. Given the very low disease failure risk and good QoL, RT remains an effective initial treatment for BALT lymphoma.