Zhen ci yan jiu = Acupuncture research · 2026
[Study on the analgesic efficacy of thumb-tack needling therapy in patients after gastric endoscopic submucosal dissection].
СтатьяРандомизированное исследованиеАннотация на английскомНазвание и аннотация: Перевод в очереди
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Ding Na, Zheng Ya, Zuo Si-Qin, Xu Ya-Nan, Liu Min, Zhen Xiao-Ling, Ji Rui
Аннотация
OBJECTIVES: To evaluate whether combining thumb-tack needle treatment with routine nursing can safely reduce pain after gastric endoscopic submucosal dissection (ESD).
METHODS: Seventy-eight patients after gastric ESD were randomized into an intervention group (n=39) and a control group (n=39), with 2 cases drop-off in the intervention group. Patients in the control group received postoperative conventional treatment. Patients in the intervention group received thumb-tack needle therapy at bilateral Zusanli (ST36) and Hegu (LI4) acupoints within 1 h after surgery in addition to conventional treatment, which lasted for 72 h. The primary outcome was the incidence of moderate-to-severe pain (visual analog scale [VAS] score ≥4) within 72 h after surgery. The secondary outcomes included pain intensity, analgesic usage rate, anxiety/depression score, numbers of gastrointestinal symptoms, surgery-related complications, and treatment-related adverse events.
RESULTS: The incidence of moderate-to-severe pain was 21.6% (8/37) in the intervention group, significantly lower (absolute difference:-24.6%;OR:0.322;95% CI:0.118-0.879;P<0.05) than that in the control group (46.2% [18/39]). Compared with the control group, the intervention group showed reduced scores in the Short-Form McGill Pain Questionnaire at the 6th, 12th, and 24th hour after surgery (P<0.01), and the median VAS score decreased by 2-3 points compared to the control group(P<0.01, P<0.001). No statistical differences were observed between the two groups in analgesic usage rate, anxiety/depression score, numbers of gastrointestinal symptoms or surgery-related complications. Two patients (5.4%) removed the needles prematurely due to psychological reasons, which did not affect clinical outcomes.
CONCLUSIONS: Thumb-tack needling therapy can effectively reduce the incidence of moderate-to-severe pain after gastric ESD and improve early postoperative pain symptoms, with a favorable safety profile.
METHODS: Seventy-eight patients after gastric ESD were randomized into an intervention group (n=39) and a control group (n=39), with 2 cases drop-off in the intervention group. Patients in the control group received postoperative conventional treatment. Patients in the intervention group received thumb-tack needle therapy at bilateral Zusanli (ST36) and Hegu (LI4) acupoints within 1 h after surgery in addition to conventional treatment, which lasted for 72 h. The primary outcome was the incidence of moderate-to-severe pain (visual analog scale [VAS] score ≥4) within 72 h after surgery. The secondary outcomes included pain intensity, analgesic usage rate, anxiety/depression score, numbers of gastrointestinal symptoms, surgery-related complications, and treatment-related adverse events.
RESULTS: The incidence of moderate-to-severe pain was 21.6% (8/37) in the intervention group, significantly lower (absolute difference:-24.6%;OR:0.322;95% CI:0.118-0.879;P<0.05) than that in the control group (46.2% [18/39]). Compared with the control group, the intervention group showed reduced scores in the Short-Form McGill Pain Questionnaire at the 6th, 12th, and 24th hour after surgery (P<0.01), and the median VAS score decreased by 2-3 points compared to the control group(P<0.01, P<0.001). No statistical differences were observed between the two groups in analgesic usage rate, anxiety/depression score, numbers of gastrointestinal symptoms or surgery-related complications. Two patients (5.4%) removed the needles prematurely due to psychological reasons, which did not affect clinical outcomes.
CONCLUSIONS: Thumb-tack needling therapy can effectively reduce the incidence of moderate-to-severe pain after gastric ESD and improve early postoperative pain symptoms, with a favorable safety profile.