Prostate Mass as a First Manifestation of Myeloid Sarcoma in a Patient With an Occult Acute Myeloid Leukemia-A Case Report.

Myeloid sarcoma (MS) with either primary or secondary prostate involvement is extremely rare. Its diagnostic is particularly challenging when prostate lesion precedes the systemic manifestation of a myeloproliferative disorder. We report such a case in a 44-year-old man with a prostate mass as a first manifestation of myeloid sarcoma associated with acute myeloid leukemia. The diagnosis of lymphoproliferative disorder was suspected in the prostate magnetic resonance imaging, and myeloid sarcoma was confirmed after transrectal ultrasound-guided prostate core biopsy.