Clinica chimica acta; international journal of clinical chemistry · 2023
Non-coding RNAs in gynecologic cancer.
СтатьяОбзорНазвание и аннотация: Перевод в очереди
Обработка статьи · этапы, ошибки и управление
Загрузка состояния…
Ошибки и ограничения
История · было → стало
Состояние обновляется каждые 5 секунд, пока блок открыт. Процент показывается только там, где известен объём работы. Пауза останавливает продолжение этапа; текущий запрос к источнику может завершиться.
Solati Arezoo, Thvimi Sina, Khatami Seyyed Hossein, Shabaninejad Zahra, Malekzadegan Yalda, Alizadeh Mehdi, Mousavi Pegah, Taheri-Anganeh Mortaza, Razmjoue Damoun, Bahmyari Sedigheh, Ghasemnejad-Berenji Hojat, Vafadar Asma, Soltani Fard Elahe, Ghasemi Hassan, Movahedpour Ahmad
Аннотация
The term "gynecologic cancer" pertains to neoplasms impacting the reproductive tissues and organs of women encompassing the endometrium, vagina, cervix, uterus, vulva, and ovaries. The progression of gynecologic cancer is linked to various molecular mechanisms. Historically, cancer research primarily focused on protein-coding genes. However, recent years have unveiled the involvement of non-coding RNAs (ncRNAs), including microRNAs, long non-coding RNAs (LncRNAs), and circular RNAs, in modulating cellular functions within gynecological cancer. Substantial evidence suggests that ncRNAs may wield a dual role in gynecological cancer, acting as either oncogenic or tumor-suppressive agents. Numerous clinical trials are presently investigating the roles of ncRNAs as biomarkers and therapeutic agents. These endeavors may introduce a fresh perspective on the diagnosis and treatment of gynecological cancer. In this overview, we highlight some of the ncRNAs associated with gynecological cancers.