A retrospective study to evaluate the work-up and follow-up of patients with monoclonal gammopathy of undetermined significance.

BACKGROUND

Monoclonal gammopathy of undetermined significance (MGUS) is a plasma cell proliferative disorder that transforms into multiple myeloma and other serious B-cell disorders at an approximate rate of 1% per year; these patients are also at increased risk for fractures.

PATIENTS AND

METHODS

We conducted a retrospective, multicenter study of 100 patients from seven community health clinics to gain a better understanding of the work-up, follow-up, and treatment of these patients.

RESULTS

MGUS patients appear to undergo inadequate work-up, follow-up, and treatment in the community setting.

CONCLUSIONS

Physicians should adhere to recently established guidelines to ensure that MGUS patients receive optimal care for this condition.