Small Bowel Neuroendocrine Tumors: An Update.

CONTEXT.—: Irving M. Ariel, MD, a pathologist at Mount Sinai Hospital in New York, published an article on small bowel neuroendocrine tumor (SB-NET) in the Archives of Pathology in 1939 titled "Argentaffin (Carcinoid) Tumors of the Small Intestine: Report of 11 Cases and Review of Literature," wherein he documented 11 cases of neuroendocrine tumors. SB-NET has since evolved in all aspects from terminology to treatment.

OBJECTIVE.—: To review the current literature on SB-NET to study the new breakthroughs of these tumors with reference to Dr Ariel's 1939 paper.

DATA SOURCES.—: The literature was reviewed to study the recent advances of SB-NET.

CONCLUSIONS.—: We found that Dr Ariel's paper stood the test of time even with all the modern innovations in the pathophysiology of SB-NET.