[Primary nontrophoblastic tumors of the placenta].

Looking from histogenetical point of view primary neoplastic alterations of placenta and umbilical cord can be divided in two main groups. First group consists of neoplasms of trophoblastic disease's origin: placental site trophoblastic tumor, choriocarcinoma and hydatidiform mole, according to most authors it not belonging to neoplasms. The second group consists of nontrophoblastic tumors, like: chorioangioma and teratoma. Hepatocellular adenoma and leiomyoma are also enclosed to the nontrophoblastic tumors. It hasn't been defined yet whether all nontrophoblastic changes in placenta or in umbilical cord should be considered as neoplasms or like pseudoneoplastic changes. Comparing to neoplasms of trophoblastic disease's origin nontrophoblastic tumors are not frequent changes to be observed, moreover they are always benign tumors. In some cases these neoplasms are asymptomatic, however clinical course of some of them may become severe. The influence of nontrophoblastic tumors on pregnancy and delivery is often underestimated. It could be observed that studies on these neoplasms are performed very seldom what may be result of their infrequent appearance and because of their asymptomatic natural history. In this study we presented an up-to date opinions about the histopathogenesis of the nontrophoblastic tumors and also their histopathological characteristics and the most common symptoms which can accompany the development of these neoplasms. An important notice is that these tumors can remain undetected during macroscopic examination of secundines.