PloS one · 2026
Construction of an experimental set up to perform full body micro cannulations of sub-millimetric vessels in an anatomical research setting.
СтатьяНазвание и аннотация: Перевод в очереди
Обработка статьи · этапы, ошибки и управление
Загрузка состояния…
Ошибки и ограничения
История · было → стало
Состояние обновляется каждые 5 секунд, пока блок открыт. Процент показывается только там, где известен объём работы. Пауза останавливает продолжение этапа; текущий запрос к источнику может завершиться.
Stouthandel Michael E J, Forouhar Danial, Debbaut Charlotte, Deviche Jurgen, De Graeve Liesl, Depypere Bernard, Meire Maarten, Adriaens Dominique, Van Hoof Tom
Аннотация
INTRODUCTION: A better 3D visualisation of the lymphatic system could provide more accurate cancer treatment approaches, but this requires contrast agent injections. Since lymphatic vessels are very small, cannulations to administer contrast agent are very difficult to perform manually. As such, a dedicated set up for lymphatic vessel micro cannulations is required.
MATERIALS AND METHODS: A micromanipulator rig for full body micro cannulations was constructed. The rig consists of an aluminium frame that can be positioned over a dissection table. It combines the micromanipulator with a sliding gantry plate and a double jointed positioning system to provide as many possible angles of approach as possible. Fluid pressure control devices and a surgical microscope can also be included in the set up.
RESULTS: Micro cannulations on a full body could successfully be performed using the micromanipulator rig. After only a short learning curve to explore the movement possibilities/range of the device, the micromanipulator rig quickly outperformed manual micro cannulations.
CONCLUSIONS: Given the short learning curve and the success rate of the micro cannulations with the micromanipulator rig, we would strongly recommend other microvascular researchers to use the micromanipulator rig for future experiments involving micro cannulations.
MATERIALS AND METHODS: A micromanipulator rig for full body micro cannulations was constructed. The rig consists of an aluminium frame that can be positioned over a dissection table. It combines the micromanipulator with a sliding gantry plate and a double jointed positioning system to provide as many possible angles of approach as possible. Fluid pressure control devices and a surgical microscope can also be included in the set up.
RESULTS: Micro cannulations on a full body could successfully be performed using the micromanipulator rig. After only a short learning curve to explore the movement possibilities/range of the device, the micromanipulator rig quickly outperformed manual micro cannulations.
CONCLUSIONS: Given the short learning curve and the success rate of the micro cannulations with the micromanipulator rig, we would strongly recommend other microvascular researchers to use the micromanipulator rig for future experiments involving micro cannulations.