Медицинская библиотека · Zhonghua liu xing bing xue za zhi = Zhonghua liuxingbingxue zazhi · 2003

[Genetic analysis of Yersinia pestis strains isolated in China].

Yu Dong-zheng, Hai Rong, Dong Xing-qi, Li Min, Xia Lian-xu, Shi Xian-ming, Wei Jian-chun, Cui Bai-zhong, Wang Peng, Sun Lian-zhi, Zhang Zhi-kai, Hu Yuan, Zhang En-min

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Аннотация

OBJECTIVE

The strains of Yersinia pestis isolated in different period and different natural foci in China were analyzed.

METHODS

Traditional and molecular biological methods were used. Rhamnose fermentation, rRNA gene copy number, nitrite reduction, and the glycerol fermentation were important characters for typing, and pulse field gel electrophoresis (PFGE) and random amplified polymorphic DNA (RAPD) profile could reflect the genetic distance between the strains.

RESULTS

The strains could be divided into 15 genetic types by those 6 characters with each of them covered an isolated geographical territories.

CONCLUSION

The characters of strains were described; the genetic relationship of different types, their evolution, and the forming and shift of plague natural foci were analyzed.

Для цитирования: Yu Dong-zheng, Hai Rong, Dong Xing-qi, Li Min, Xia Lian-xu, Shi Xian-ming, Wei Jian-chun, Cui Bai-zhong, Wang Peng, Sun Lian-zhi, Zhang Zhi-kai, Hu Yuan, Zhang En-min. [Genetic analysis of Yersinia pestis strains isolated in China].. Zhonghua liu xing bing xue za zhi = Zhonghua liuxingbingxue zazhi. 2003.

Предметные рубрики MeSH

China Databases, Genetic Electrophoresis, Gel, Pulsed-Field Genetic Drift Geography Mutation Random Amplified Polymorphic DNA Technique Yersinia pestis

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