Prenatal Diagnosis and Classification of Type I Persistent Left Superior Vena Cava.

OBJECTIVE

This study aimed to assess the utility of two-dimensional (2D) ultrasonography in diagnosing and classifying fetal type I persistent left superior vena cava (PLSVC).

METHODS

The diameter (D1) of the coronary sinus (CS) was measured in the four-chamber view and the diameter (D2) of the PLSVC was measured in the three-vessel trachea view; the ratio of the diameter of CS to PLSVC (D1/D2) and the ratio of gestational week (GA)/D1 and GA/D2 were calculated to analyze the correlation between measurement and classification of type I PLSVC.

RESULTS

Compared the parameter of Ia and Ib Group, the differences in D1, D2, GA/D1, and GA/D2 were statistically significant (P < .05). D1 and D2 are independent factors for the differential diagnosis of type I PLSVC, with odds ratios (OR) of 5.397 and 2.661, respectively, and both are statistically significant (P < .05). The nomogram model exhibited superior performance in diagnosing type I PLSVC, with the highest AUC value of 0.853, a sensitivity of 96.55%, and a specificity of 66.25%.

CONCLUSION

The combination of D1, D2, GA/D1, and GA/D2 is valuable for diagnosing and classifying fetal type I PLSVC, demonstrating significant clinical application value.