Biomaterials in pancreatic surgery: progress and challenges in preoperative, intraoperative and postoperative care.

Pancreatic surgery is frequently associated with exceptionally high risks due to the intricate anatomical structure, and elevated enzymatic activity, which can lead to severe postoperative complications. With deep integration of material science and clinical medicine, biomaterials have been progressively applied in pancreatic surgery across the entire perioperative period, not only improved the sensitivity and specificity of diagnosis but also prevent postoperative complications and accelerated rehabilitation. Thus, this review systematically summarizes state-of-art development, efficacy, safety, challenges and perspective of biomaterials when they are applied in pancreatic surgery at preoperative, intraoperative and postoperative stages, which not only help clinicians choose materials-derived products for their surgical operations, but also provide insights for material scientists into developing advanced materials for pancreatic surgery.