Outcomes of fetuses with severe diaphragmatic hernia after fetal endoluminal tracheal occlusion treatment: A series of case reports.

OBJECTIVE

To explore outcomes of fetuses with severe congenital diaphragmatic hernia (CDH) after fetal endoluminal tracheal occlusion (FETO) treatment.

CASE REPORT: Fetuses diagnosed with severe CDH and taken FETO for intrauterine treatment from January 2020 to December 2023 were recruited. There was no significant difference in general conditions, as well as O/E LHR and measurements related to CDH (p > 0.05). All babies were born prematurely. One got poor Apgar score and died soon after birth and 3 died after treatment in NICU for some time. Only one associated with congenital cystic adenomatoid malformation (CCAM) was survived and got good outcome after long time follow-up. It seemed CCAM associated occupying a part volume of left thorax which may help to protect abdominal organs from herniating.

CONCLUSION

FETO treatment may not improve the survival rate of severe CDH significantly, but associated with CCAM may helpful to protect abdominal organs from herniating.