Liposarcoma of the Arygepiglottic Fold: Teaching point: A mosaic tumor pattern mixing fatty and non-fatty enhancing components suggests liposarcoma, even in very rare locations such as neck spaces.

Liposarcoma of the larynx and hypopharynx is very rare. Computed tomography (CT) and magnetic resonance imaging (MRI) examinations may synergistically disclose suggestive features of a fat-containing tumor with non-fatty enhancing sub-areas. Diagnosis relies on histological examination of a biopsic specimen. This rare pathology should ultimately be kept in mind when dealing with an laryngeal/hypopharyngeal mass.