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Войти в исследования ASM case reports · 2025
Multisite infection with Austrian syndrome caused by non-vaccine pneumococcal serotype-case report.
Клинический случайСтатьяНазвание и аннотация: Перевод в очереди
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Børrild Frederik Juel Pontoppidan, Fosbøl Emil, Roed Casper, Hornbæk Øvre Melissa, Brander Eriksen Helle, Kraef Christian, Helweg-Larsen Jannik, Harboe Zitta Barrella, Ekenberg Christina
Аннотация
BACKGROUND: Although rare, Austrian syndrome remains a life-threatening triad consisting of pneumonia, endocarditis, and meningitis caused by Streptococcus pneumoniae.
CASE SUMMARY: We present a case of Austrian syndrome, further complicated by spondylodiscitis and endophthalmitis, in an immunocompromised male receiving methotrexate treatment for rheumatoid arthritis. The infection was caused by a non-vaccine pneumococcal serotype (23B). Susceptibility testing showed reduced susceptibility towards benzylpenicillin, an uncommon finding in Denmark.
CONCLUSION: This case illustrates some of the challenges faced in managing invasive pneumococcal disease and underlines the importance of continued awareness of this disease, particularly in immunocompromised patients.
CASE SUMMARY: We present a case of Austrian syndrome, further complicated by spondylodiscitis and endophthalmitis, in an immunocompromised male receiving methotrexate treatment for rheumatoid arthritis. The infection was caused by a non-vaccine pneumococcal serotype (23B). Susceptibility testing showed reduced susceptibility towards benzylpenicillin, an uncommon finding in Denmark.
CONCLUSION: This case illustrates some of the challenges faced in managing invasive pneumococcal disease and underlines the importance of continued awareness of this disease, particularly in immunocompromised patients.