Emerging infectious diseases · 2025
Pneumococcal Septic Arthritis among Adults, France, 2010-2018.
СтатьяНазвание и аннотация: Перевод в очереди
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Hamdad Farida, El Bayeh Nadim, Auger Gabriel, Peuchant Olivia, Wallet Frédéric, Ruimy Raymond, Reibel Florence, Martin Christian, Ploy Marie-Cécile, Robin Frédéric, Laurens Chrislène, Lanotte Philippe, Kempf Marie, Tetu Jennifer, Revillet Hélène, Patry Isabelle, Cailloux Philippe, Azouaou Mélissa, Varon Emmanuelle, Duhaut Pierre, Lozniewski Alain, Cattoir Vincent
Аннотация
Streptococcus pneumoniae infection is considered an uncommon cause of arthritis in adults. To determine the clinical and microbiological characteristics of pneumococcal septic arthritis, we retrospectively studied a large series of cases among adult patients during the 2010-2018 conjugate vaccine era in France. We identified 110 patients (56 women, 54 men; mean age 65 years), and cases included 82 native joint infections and 28 prosthetic joint infections. Most commonly affected were the knee (50/110) and hip (25/110). Concomitant pneumococcal infections were found in 37.2% (38/102) and bacteremia in 57.3% (55/96) of patients, and underlying conditions were noted for 81.4% (83/102). Mortality rate was 9.4% (8/85). The proportion of strains not susceptible to penicillin was 29.1% (32/110). Of the 55 serotyped strains, 31 (56.4%) were covered by standard pneumococcal vaccines; however, several nonvaccine serotypes (mainly 23B, 24F, and 15A) had emerged, for which susceptibility to β-lactams was low.