Studies on viral arthritis (teno-synovitis) in Italy.

Three of several virus isolates made from different groups of chickens affected with arthritis were serially passaged in chicken embryos, and then cultured on chicken kidney cells with the production of cytopathic effects and development of syncytia. Resistance to inactivating agents and electron microscopic features showed their relationship to reoviruses. By the agar gel diffusion test the isolates were shown to be serologically related to each other and to 2 American strains. A tissue suspension from infected embryos when inoculated into the footpad of one to 15 day-old chicks reproduced arthritis.