Magnetic resonance in medicine · 2017
Quantitative magnetization transfer ultrashort echo time imaging using a time-efficient 3D multispoke Cones sequence.
СтатьяПоддержка NIH: внешняя программаПоддержка исследования: вне правительства СШАПоддержка правительства СШАНазвание и аннотация: Перевод в очереди
Обработка статьи · этапы, ошибки и управление
Загрузка состояния…
Ошибки и ограничения
История · было → стало
Состояние обновляется каждые 5 секунд, пока блок открыт. Процент показывается только там, где известен объём работы. Пауза останавливает продолжение этапа; текущий запрос к источнику может завершиться.
Ma Ya-Jun, Chang Eric Y, Carl Michael, Du Jiang
Аннотация
PURPOSE: To accelerate the quantitative ultrashort echo time imaging using a time-efficient 3D multispoke Cones sequence with magnetization transfer (3D UTE-Cones-MT) and signal modeling.
THEORY AND METHODS: A 3D UTE-Cones-MT acquisition scheme with multispoke per MT preparation and a modified rectangular pulse (RP) approximation was developed for two-pool MT modeling of macromolecular and water components including their relative fractions, relaxation times and exchange rates. Numerical simulation and cadaveric specimens, including human Achilles tendon and bovine cortical bone, were investigated using a clinical 3T scanner.
RESULTS: Numerical simulation showed that the modified RP model provided accurate estimation of MT parameters when multispokes were acquired per MT preparation. For the experiment with the Achilles tendon and cortical bone samples, the macromolecular fractions were 20.4 ± 2.0% and 59.4 ± 5.3%, respectively.
CONCLUSION: The 3D multispoke UTE-Cones-MT sequence can be used for fast volumetric assessment of macromolecular and water components in short T2 tissues. Magn Reson Med 79:692-700, 2018. © 2017 International Society for Magnetic Resonance in Medicine.
THEORY AND METHODS: A 3D UTE-Cones-MT acquisition scheme with multispoke per MT preparation and a modified rectangular pulse (RP) approximation was developed for two-pool MT modeling of macromolecular and water components including their relative fractions, relaxation times and exchange rates. Numerical simulation and cadaveric specimens, including human Achilles tendon and bovine cortical bone, were investigated using a clinical 3T scanner.
RESULTS: Numerical simulation showed that the modified RP model provided accurate estimation of MT parameters when multispokes were acquired per MT preparation. For the experiment with the Achilles tendon and cortical bone samples, the macromolecular fractions were 20.4 ± 2.0% and 59.4 ± 5.3%, respectively.
CONCLUSION: The 3D multispoke UTE-Cones-MT sequence can be used for fast volumetric assessment of macromolecular and water components in short T2 tissues. Magn Reson Med 79:692-700, 2018. © 2017 International Society for Magnetic Resonance in Medicine.