[Spondylarthropathies].

Spondylarthropathies include the ankylosing spondylitis, psoriatic arthritis, reactive arthritis, arthritis of inflammatory bowel disease (Crohn disease, ulcerative colitis), some juvenile arthritis and undifferenciated spondylarthropathies. These diseases are linked together by a basic elementary lesion, enthesitis, common clinical and radiological features (sacroiliitis, spondylitis, peripheral arthritis, extra-articular manifestations), and association with HLA B27 antigen. Prevalence of spondylarthropathies in France is estimated at 0.3%, with no difference between women and men. Therapeutic option associate physical therapy and anti-inflammatory drugs. In case of insufficient efficacy of these conventional drugs, TNFalpha antagonist therapy can be used in axial forms, after disease modifying drugs in peripheral forms.