Ulcerative Colitis in a Patient With Auricular Chondritis and Sweet Syndrome: A Rare Case.

Relapsing polychondritis (RP) is a rare immune-mediated inflammatory disorder primarily affecting cartilaginous tissues throughout the body that may involve other connective tissues. The initial manifestation is often auricular chondritis, and cutaneous presentations are relatively uncommon. Approximately 30% of RP cases have an association with autoimmune diseases, but it is incredibly rare for there to be any coexistence with inflammatory bowel disease (IBD). Sweet syndrome (SS), which is also known as acute febrile neutrophilic dermatosis, also has an association with autoimmune disorders and is considered to be an incredibly rare extraintestinal IBD manifestation. In this article, a case of a patient simultaneously presenting with auricular chondritis, ulcerative colitis (UC), and SS, which had an effective response to systemic corticosteroid therapy is reported. As far as we are aware, this is the first reported case of the coexistence of these three disorders, and it will provide valuable insights into the diagnosis and management of RP that is complicated by UC and other associated conditions.