Vasculitis in an Infant Born to a Mother With Longstanding Cutaneous Polyarteritis Nodosa: A Case Report and Review of Literature.

We present a neonate born to a mother with a known diagnosis of cutaneous polyarteritis nodosa (cPAN) who presented with acrocyanosis on the first day of life, which progressed to livedo reticularis and eventual digital necrosis and autoamputation. Our case, along with several previously reported cases, indicates that maternal vasculitis flares or new-onset maternal vasculitis during pregnancy may contribute to the development of neonatal vasculitis. Of note, acral necrosis appears to be a unique disease manifestation in neonates, not often seen in older patients. This report aims to increase patient and clinician awareness of this rare condition.