Osteoporosis international : a journal established as result of cooperation between the European Foundation for Osteoporosis and the National Osteoporosis Foundation of the USA · 2026
Trends of clinical vertebral and hip fractures following local government involvement in fracture prevention from 2015 to 2021 in Kure, Japan.
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Mizuno Toshiyuki, Tsukamoto Manabu, Teramoto Hidefumi, Hamasaki Takahiko, Shirakawa Taizan, Nakagawa Tsuyoshi, Yamasaki Takuma, Tsukisaka Junya, Adachi Nobuo, Fujiwara Saeko, Okimoto Nobukazu
Аннотация
UNLABELLED: Community-wide Fracture Liaison Services and educational outreach to local physicians on osteoporosis can effectively reduce the fragility fracture burden at the population level in a super-aged society.
PURPOSE: Effective prevention of osteoporosis and fractures requires not only implementing a Fracture Liaison Service (FLS) but also enhancing osteoporosis awareness among local physicians, residents, and the municipality. We examined the impact of multidisciplinary, municipality-supported FLS and osteoporosis awareness activities on the incidence of clinical vertebral and hip fractures in a rapidly ageing urban Japanese population.
METHODS: We conducted a population-based pre-post observational study of residents aged ≥ 65 years in Kure, Japan, following the introduction of community-wide FLS and osteoporosis awareness activities. Residents were enrolled in the National Health Insurance or Senior Elderly Care System between 2015 and 2021. Fracture events were identified using insurance claims data and ICD/treatment codes.
RESULTS: Overall, the incidence of clinical vertebral fractures tended to increase until 2017 and then tended to decrease thereafter; the incidence of hip fractures tended to decrease after 2017 in females but not in males. Compared with the incidence in 2017, the age-sex-adjusted incidence ratio was 0.76 (95% CI 0.70-0.83) for clinical vertebral fractures and 0.87 (95% CI 0.78-0.96) for hip fractures in 2015. In 2021, the incidence ratio was 0.89 (95% CI 0.82-0.96) for clinical vertebral fractures and 0.85 (95% CI 0.76-0.94) for hip fractures. During this period, an increase in the number of prescriptions and changes in the prescribing patterns were observed.
CONCLUSIONS: Significant reductions in the incidence of both clinical vertebral and hip fractures among women were demonstrated after the launch of a comprehensive fracture prevention project supported by the local government.
PURPOSE: Effective prevention of osteoporosis and fractures requires not only implementing a Fracture Liaison Service (FLS) but also enhancing osteoporosis awareness among local physicians, residents, and the municipality. We examined the impact of multidisciplinary, municipality-supported FLS and osteoporosis awareness activities on the incidence of clinical vertebral and hip fractures in a rapidly ageing urban Japanese population.
METHODS: We conducted a population-based pre-post observational study of residents aged ≥ 65 years in Kure, Japan, following the introduction of community-wide FLS and osteoporosis awareness activities. Residents were enrolled in the National Health Insurance or Senior Elderly Care System between 2015 and 2021. Fracture events were identified using insurance claims data and ICD/treatment codes.
RESULTS: Overall, the incidence of clinical vertebral fractures tended to increase until 2017 and then tended to decrease thereafter; the incidence of hip fractures tended to decrease after 2017 in females but not in males. Compared with the incidence in 2017, the age-sex-adjusted incidence ratio was 0.76 (95% CI 0.70-0.83) for clinical vertebral fractures and 0.87 (95% CI 0.78-0.96) for hip fractures in 2015. In 2021, the incidence ratio was 0.89 (95% CI 0.82-0.96) for clinical vertebral fractures and 0.85 (95% CI 0.76-0.94) for hip fractures. During this period, an increase in the number of prescriptions and changes in the prescribing patterns were observed.
CONCLUSIONS: Significant reductions in the incidence of both clinical vertebral and hip fractures among women were demonstrated after the launch of a comprehensive fracture prevention project supported by the local government.