Terapevticheskii arkhiv · 2001
[Post-respiratory infection reactive arthritis--etiology, clinical and laboratory characteristics and early prognosis].
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Dimov D, Zhutev I, Raichev R, Martinova F, Khristov M, Martinov S
Аннотация
AIM: To study etiology, clinico-laboratory characteristics and early prognosis of reactive arthritis developing after respiratory infections (priReA).
MATERIAL AND METHODS: Blood samples from 69 priReA patients aged 17-45 years were examined for specific antibodies to 28 bacterial and viral infectious agents, and antigens of group HLA-B7-CREG (B7, B13, B22, B27, B40, B73, Cw2). The test were made in hospital and 3 months after the patients' discharge.
RESULTS: The priReA respiratory etiology was discovered in 31 patients, urogenital--in 14 cases and enterocolitic one--in 7 patients. Streptococcus and pneumoneal chlamydia cause priReA most frequently. HLA-B40 carriers are more predisposed to priReA. priReA runs with less frequent Reiter's syndrome and lesions of axial and extraarticular structures, better early prognosis.
CONCLUSION: In young patients with early ReA respiratory etiology is observed more frequently than urogenital and enterocolitic ones. Compared to other kinds of ReA, priReA demonstrates some genetic, clinical and prognostic peculiarities.
MATERIAL AND METHODS: Blood samples from 69 priReA patients aged 17-45 years were examined for specific antibodies to 28 bacterial and viral infectious agents, and antigens of group HLA-B7-CREG (B7, B13, B22, B27, B40, B73, Cw2). The test were made in hospital and 3 months after the patients' discharge.
RESULTS: The priReA respiratory etiology was discovered in 31 patients, urogenital--in 14 cases and enterocolitic one--in 7 patients. Streptococcus and pneumoneal chlamydia cause priReA most frequently. HLA-B40 carriers are more predisposed to priReA. priReA runs with less frequent Reiter's syndrome and lesions of axial and extraarticular structures, better early prognosis.
CONCLUSION: In young patients with early ReA respiratory etiology is observed more frequently than urogenital and enterocolitic ones. Compared to other kinds of ReA, priReA demonstrates some genetic, clinical and prognostic peculiarities.