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DOI 10.1097/mnm.0000000000002177

Медицинская библиотека · Nuclear medicine communications · 2026

Impact of single photon emission computed tomography/computed tomography bone scintigraphy on the clinical management of patients with recurrent pain post spinal fusion.

Ozdoeva Daisy, Bleyen Joris, Harth André, Van Den Bossche Bieke, Mertens Jeroen, Berwouts Dieter, Baert Matthieu, Vermeire Nadine, Michielsen Geert, Coessens Ronald, Matton Tom, Baetslé Amaury, Vermeulen Arne, Vandereycken Jan, Hendrickx Jan, Baelde Nick, Lagae Philippe, Cortier Jeroen, Verstraeten Valerie, Lambert Bieke

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Аннотация

OBJECTIVE

Persistent or recurrent pain following spinal fusion surgery presents a significant diagnostic and therapeutic challenge. This study aims to assess the clinical utility of single photon emission computed tomography/computed tomography (SPECT/CT) bone scintigraphy in identifying pain generators and guiding management decisions in patients with pain occurring or persisting following spinal fusion surgery.

MATERIALS AND

METHODS

We conducted a retrospective analysis of patients who underwent a SPECT/CT 6-24 months after cervical or lumbar spinal fusion. The impact of SPECT/CT findings on clinical decision-making was evaluated based on postoperative records. We also examined a subset of nonunion cases receiving multiple SPECT/CTs over time to assess changes in bone remodeling patterns at the fusion site.

RESULTS

A total of 114 SPECT/CT scans (94 lumbar and 20 cervical) were reviewed in 106 patients and revealed pseudarthrosis with or without screw loosening (51%), adjacent level degeneration of facet joint or endplates (19%), screw irritation (12%), and extraspinal pain sources (5%). Positive SPECT/CT reports had an impact on the subsequent clinical management in 69% of cases. In 36 patients with nonunion and serial SPECT/CT scans over time, 94% showed unchanged bone remodeling patterns over time.

CONCLUSION

SPECT/CT bone scintigraphy significantly contributed to clinical decision-making in the majority of patients with pain following spinal fusion. It effectively identified pain generators thereby guiding appropriate treatments. Furthermore, the imaging modality demonstrated a high degree of consistency in bone remodeling patterns over time. Our findings underscore the valuable role of SPECT/CT as a diagnostic adjunct in complex cases of failed back surgery syndrome.

Для цитирования: Ozdoeva Daisy, Bleyen Joris, Harth André, Van Den Bossche Bieke, Mertens Jeroen, Berwouts Dieter, Baert Matthieu, Vermeire Nadine, Michielsen Geert, Coessens Ronald, Matton Tom, Baetslé Amaury, Vermeulen Arne, Vandereycken Jan, Hendrickx Jan, Baelde Nick, Lagae Philippe, Cortier Jeroen, Verstraeten Valerie, Lambert Bieke. Impact of single photon emission computed tomography/computed tomography bone scintigraphy on the clinical management of patients with recurrent pain post spinal fusion.. Nuclear medicine communications. 2026. DOI: 10.1097/mnm.0000000000002177.

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