Impact of lymph node ratio and number of lymph node metastases on survival and recurrence in laryngeal squamous cell carcinoma.
Обработка статьи · этапы, ошибки и управление
Ошибки и ограничения
История · было → стало
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Molteni Gabriele, Nocini Riccardo, Mattioli Francesco, Nakayama Meijin, Dedivitis Rogerio A, Mannelli Giuditta, Crosetti Erika, Chiesa-Estomba Carlos Miguel, Sistiaga-Suarez Jon A, Giordano Leone, Galli Andrea, Lionello Marco, Mercante Giuseppe, Ralli Massimo, Fermi Matteo, Klein-Rodríguez Alejandro, Mayo-Yáñez Miguel, Serafini Edoardo, Pirola Francesca, Paderno Alberto, Cambria Francesca, Oridate Nobuhiko, Sano Daisuke, Boscolo-Rizzo Paolo, Marcuzzo Alberto Vito, Parrinello Giampiero, Marchi Filippo, Saibene Alberto Maria, Tucciarone Manuel, Viscasillas Guillem, Zeleník Karol, Ramos Daniel Marin, Palacios-Garcia Jose, Tirelli Giancarlo, Pellini Raul, Paludetti Gaetano, Galli Jacopo, Rossi Giorgia, De Vincentiis Marco, Cernea Claudio Roberto, Spriano Giuseppe, Bussi Mario, Peretti Giorgio, Succo Giovanni, Piazza Cesare, Bertolin Andy, Kowalski Luiz Paulo, Presutti Livio, Sacchetto Andrea
Аннотация
MATERIALS AND METHODS: We conducted a retrospective multicenter international study involving 24 Otorhinolaryngology-Head and Neck Surgery divisions. Disease-specific survival (DSS) and disease-free survival (DFS) were evaluated as the main outcomes. The curves for DSS and DFS according to NPLN and LNR were analyzed to identify significant variations and establish specific cut-off values.
RESULTS: 2507 patients met the inclusion criteria. DSS and DFS were significantly different in the groups of patients stratified according to LNR and NPLN. The 5-year DSS and DFS based on LNR and NPLN demonstrated an improved ability to stratify patients when compared to pN staging.
CONCLUSION: Our data demonstrate the potential prognostic value of NPLN and LNR in laryngeal squamous cell carcinoma.