Neurosurgical focus · 2026
Does surgical treatment of grade 2 spondylolisthesis have sustained improvement in postoperative outcomes regardless of age? A Spine CORe™ analysis of QOD data.
Сравнительное исследованиеСтатьяМногоцентровое исследованиеМногоцентровое исследованиеПоддержка исследования: вне правительства СШАНазвание и аннотация: Перевод в очереди
Обработка статьи · этапы, ошибки и управление
Загрузка состояния…
Ошибки и ограничения
История · было → стало
Состояние обновляется каждые 5 секунд, пока блок открыт. Процент показывается только там, где известен объём работы. Пауза останавливает продолжение этапа; текущий запрос к источнику может завершиться.
Kharas Natasha, Robayo Anthony, Wang Evan, Turner Jay D, Uribe Juan S, Asher Anthony L, Kim Paul K, Shaffrey Christopher I, Gottfried Oren N, Potts Eric A, Alentado Vincent J, Bydon Mohamad, Park Paul, Wang Michael Y, Glassman Steven D, Djurasovic Mladen, Foley Kevin T, Upadhyaya Cheerag D, Yee Timothy J, Chan Andrew K, Chou Dean, Mummaneni Praveen V, Yen Chun-Po, Bisson Erica F, Haid Regis, Virk Michael S, Fu Kai-Ming G
Аннотация
OBJECTIVE: Surgical intervention for grade 2 lumbar spondylolisthesis is routinely performed, but outcomes in older patients, in whom the disease is most prevalent, remain poorly understood. The aim of this study was to compare patient-reported surgical outcomes between age groups (< 65 years of age vs ≥ 65 years of age) with 5 years of follow-up. The authors hypothesized that patients would have sustained improvement in outcomes in response to surgical treatment for grade 2 spondylolisthesis regardless of age.
METHODS: The multicenter prospectively collected Quality Outcomes Database by the Spine CORe™ study group was retrospectively analyzed for patients who underwent arthrodesis for grade 2 lumbar spondylolisthesis. Across 14 high-enrolling sites, 328 patients with 81% follow-up were identified. Baseline and postoperative 3-month, 1-year, 2-year, and 5-year outcomes including numeric rating scale (NRS) back pain (score 0-10), NRS leg pain (score 0-10), Oswestry Disability Index (ODI), EQ-5D scores, and patient satisfaction using the North American Spine Society (NASS) index, were evaluated. These outcomes were compared between younger (< 65 years of age, n = 188) and older (≥ 65 years of age, n = 140) age groups using Wilcoxon rank-sum tests.
RESULTS: EQ-5D and ODI scores were significantly improved postoperatively in the younger and older age groups (p < 0.001). ODI scores were not significantly different between the age groups at baseline (p = 0.37) or postoperatively at any time point (p > 0.05). EQ-5D scores were not significantly different between the younger and older patient groups at baseline (p = 0.47) or postoperatively at any time point (p > 0.05). NRS leg pain (p = 0.68) and back pain (p = 0.45) scores were not significantly different at baseline across age groups. NRS leg pain was not significantly different postoperatively (p > 0.05). Older patients had lower back pain scores (p = 0.03) at 3 months postoperatively, but not at any other time points (p > 0.05). Leg and back pain scores improved postoperatively up to 5 years of follow-up in all patients (p < 0.0001). A majority of the younger (83.5%) and older (89.5%) patients reported satisfaction with their surgical outcome up to 5 years after surgery, and postoperative NASS satisfaction scores were not significantly different between the younger and older age groups at any time point (p > 0.05).
CONCLUSIONS: In response to surgical treatment, patients over 65 years of age have significant improvements similar to those of younger patients. Surgical treatment is a viable option for improvement regardless of age.
METHODS: The multicenter prospectively collected Quality Outcomes Database by the Spine CORe™ study group was retrospectively analyzed for patients who underwent arthrodesis for grade 2 lumbar spondylolisthesis. Across 14 high-enrolling sites, 328 patients with 81% follow-up were identified. Baseline and postoperative 3-month, 1-year, 2-year, and 5-year outcomes including numeric rating scale (NRS) back pain (score 0-10), NRS leg pain (score 0-10), Oswestry Disability Index (ODI), EQ-5D scores, and patient satisfaction using the North American Spine Society (NASS) index, were evaluated. These outcomes were compared between younger (< 65 years of age, n = 188) and older (≥ 65 years of age, n = 140) age groups using Wilcoxon rank-sum tests.
RESULTS: EQ-5D and ODI scores were significantly improved postoperatively in the younger and older age groups (p < 0.001). ODI scores were not significantly different between the age groups at baseline (p = 0.37) or postoperatively at any time point (p > 0.05). EQ-5D scores were not significantly different between the younger and older patient groups at baseline (p = 0.47) or postoperatively at any time point (p > 0.05). NRS leg pain (p = 0.68) and back pain (p = 0.45) scores were not significantly different at baseline across age groups. NRS leg pain was not significantly different postoperatively (p > 0.05). Older patients had lower back pain scores (p = 0.03) at 3 months postoperatively, but not at any other time points (p > 0.05). Leg and back pain scores improved postoperatively up to 5 years of follow-up in all patients (p < 0.0001). A majority of the younger (83.5%) and older (89.5%) patients reported satisfaction with their surgical outcome up to 5 years after surgery, and postoperative NASS satisfaction scores were not significantly different between the younger and older age groups at any time point (p > 0.05).
CONCLUSIONS: In response to surgical treatment, patients over 65 years of age have significant improvements similar to those of younger patients. Surgical treatment is a viable option for improvement regardless of age.