Communications medicine · 2026
Multimorbidity in adolescents in sub-Saharan Africa: a systematic review.
СтатьяНазвание и аннотация: Перевод в очереди
Обработка статьи · этапы, ошибки и управление
Загрузка состояния…
Ошибки и ограничения
История · было → стало
Состояние обновляется каждые 5 секунд, пока блок открыт. Процент показывается только там, где известен объём работы. Пауза останавливает продолжение этапа; текущий запрос к источнику может завершиться.
Nzvere F P, Iduye D, Okello E, Bernays S, Ross D A, Ferrand R A, Simms V, Doyle A M
Аннотация
BACKGROUND: Individuals living with two or more long-term health conditions, known as multimorbidity, experience poorer physical and mental well-being due to the incremental effect of co-existing conditions. Research on multimorbidity mainly focuses on adults and rarely on adolescents (10-19 years), especially in Africa. We aimed to describe the prevalence of adolescent multimorbidity in Sub-Saharan Africa.
METHODS: We conducted a PROSPERO-registered systematic review (CRD42024513430), searching five databases (Medline, EMBASE, Global Health, SCOPUS, PsycINFO, PsycEXTRA, and Africa Index Medicus) for observational studies published in 2000-2024. Studies were eligible if they assessed the prevalence of two or more chronic co-existing conditions (multimorbidity) in adolescents from the general population in Sub-Saharan Africa. Two reviewers independently screened studies, extracted data, and assessed risk of bias.
RESULTS: Here we show that 12 studies meet the inclusion criteria, out of 2824 potential studies. Most studies have a low to moderate risk of bias and were conducted within the last decade in community and/or school settings. The studies only measure multimorbidity from a limited set of conditions: allergic, malnutrition, cardiometabolic diseases, e.g. hypertension and diabetes only and cardiometabolic diseases plus HIV/tuberculosis. No study includes common mental disorders. Most individual conditions are objectively measured and have low prevalences ( < 10%). Multimorbidity prevalence ranges from 0.0 to 13.8% and varies by the conditions measured.
CONCLUSION: This systematic review identified only 12 eligible studies, with substantial methodological heterogeneity limiting the comparability and generalizability of multimorbidity estimates. Further adolescent-specific research focusing on enhancing the measurement of multimorbidity of conditions commonly affecting adolescents is required to allow accurate estimates and to inform healthcare provision.
METHODS: We conducted a PROSPERO-registered systematic review (CRD42024513430), searching five databases (Medline, EMBASE, Global Health, SCOPUS, PsycINFO, PsycEXTRA, and Africa Index Medicus) for observational studies published in 2000-2024. Studies were eligible if they assessed the prevalence of two or more chronic co-existing conditions (multimorbidity) in adolescents from the general population in Sub-Saharan Africa. Two reviewers independently screened studies, extracted data, and assessed risk of bias.
RESULTS: Here we show that 12 studies meet the inclusion criteria, out of 2824 potential studies. Most studies have a low to moderate risk of bias and were conducted within the last decade in community and/or school settings. The studies only measure multimorbidity from a limited set of conditions: allergic, malnutrition, cardiometabolic diseases, e.g. hypertension and diabetes only and cardiometabolic diseases plus HIV/tuberculosis. No study includes common mental disorders. Most individual conditions are objectively measured and have low prevalences ( < 10%). Multimorbidity prevalence ranges from 0.0 to 13.8% and varies by the conditions measured.
CONCLUSION: This systematic review identified only 12 eligible studies, with substantial methodological heterogeneity limiting the comparability and generalizability of multimorbidity estimates. Further adolescent-specific research focusing on enhancing the measurement of multimorbidity of conditions commonly affecting adolescents is required to allow accurate estimates and to inform healthcare provision.