Therapeutic Plasma Exchange in a 15-kg Child With Atypical Hemolytic Uremic Syndrome: A Case Report.

Atypical hemolytic uremic syndrome (aHUS) is one of the thrombotic microangiopathy (TMA) syndromes characterized by thrombocytopenia, Coombs-negative hemolytic anemia, and renal dysfunction without evidence of Shiga toxin-producing Escherichia coli (E. coli) (STEC) or thrombotic thrombocytopenic purpura (TTP). aHUS is a rare, potentially fatal entity. We present a case of a six-year-old male with vomiting and abdominal pain who developed hematuria and jaundice, along with acute kidney injury (AKI). The patient was diagnosed with aHUS and managed with plasma infusions and exchange, immunosuppression, hemodialysis, and associated kidney-protective measures. He successfully achieved remission and was discharged after a prolonged hospital stay.