Clinical laboratory · 2026
A Case of Antinuclear Antibody-Negative Dermatomyositis with Interstitial Lung Disease.
Клинический случайСтатьяНазвание и аннотация: Перевод в очереди
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Qian Ying, Xie Kejie
Аннотация
BACKGROUND: Antinuclear antibody (ANA) is important for the diagnosis of autoimmune diseases. When ANA is positive, further specific autoantibody tests are needed to make a definite diagnosis.
METHODS: This article reports a case of a patient with an autoimmune disease who had inconsistent results in the detection of antinuclear antibodies by indirect immunofluorescence assay (IIFA) and linear immunoblotting assay (LIA).
RESULTS: This patient presented with negative ANA and positive anti-SSA/Ro52.
CONCLUSIONS: IIF-ANA negative and LIA-ANAS positive exists in clinical tests. The combination of IIFA and LIA is important.
METHODS: This article reports a case of a patient with an autoimmune disease who had inconsistent results in the detection of antinuclear antibodies by indirect immunofluorescence assay (IIFA) and linear immunoblotting assay (LIA).
RESULTS: This patient presented with negative ANA and positive anti-SSA/Ro52.
CONCLUSIONS: IIF-ANA negative and LIA-ANAS positive exists in clinical tests. The combination of IIFA and LIA is important.