Unmasking neuroinvasive melioidosis: Insights from Burkholderia pseudomallei cases in an Indian neurocenter - A case series.

Neuromelioidosis, a rare but severe complication of melioidosis caused by B. pseudomallei, is associated with a high mortality rate. These cases exhibited diverse neurological manifestations, including quadriparesis, hemiparesis, encephalopathy, and abscess formation. All cases were confirmed through culture and received appropriate antibiotic therapy. India is considered to have significant underreporting of melioidosis, leading to delayed diagnosis and treatment challenges. Early identification and initiation of antimicrobial therapy are crucial to improve patient outcomes. Clinicians should maintain a high index of suspicion for B. pseudomallei in neurological infections to minimize diagnostic delays.