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DOI 10.14444/8817

Медицинская библиотека · JPMA. The Journal of the Pakistan Medical Association · 2018

Role of melatonin in management of hypoxic ischaemic encephalopathy in newborns: A randomized control trial.

Ghellab Okba, Seas Andreas, Shaker Eric, Bartlett Alyssa M, Paturu Mounica, Calebrese Evan, Abd-El-Barr Muhammad M

СтатьяРандомизированное исследованиеПеревод в очереди

Аннотация

BACKGROUND

Minimally invasive transfacet transforaminal lumbar interbody fusion (TF-TLIF) offers advantages over open approaches, including reduced tissue disruption and faster recovery. However, limited visualization increases the risk of neural injury, particularly to the exiting nerve roots and thecal sac.

INNOVATION: This case report illustrates the integration of augmented reality (AR) to enhance real-time visualization during TF-TLIF. A 53-year-old man with symptomatic L4 to L5 spondylolisthesis underwent AR-assisted TF-TLIF. Preoperative imaging included magnetic resonance imaging, computed tomography, and advanced neurography sequences (Multi-Echo iN Steady-state Acquisition, Short Tau Inversion Recovery, and Dixon T1), which were used to generate a 3D model of critical anatomy. A safe transfacet trajectory was planned preoperatively and overlaid onto the surgical field through the operative microscope, using intraoperative 3D imaging for registration. Intraoperative neurophysiological monitoring complemented visual guidance.

CLINICAL RELEVANCE: AR enabled continuous visualization of neural structures during drilling, discectomy, and cage placement. The patient had no complications and was discharged on postoperative day 1 without new neurological deficits. While limited to a single case, this report demonstrates the feasibility of AR-assisted TF-TLIF. This technology may serve as a promising adjunct in minimally invasive spine surgery. Further studies are needed to assess the impact on efficiency and outcomes.

Для цитирования: Ghellab Okba, Seas Andreas, Shaker Eric, Bartlett Alyssa M, Paturu Mounica, Calebrese Evan, Abd-El-Barr Muhammad M. Role of melatonin in management of hypoxic ischaemic encephalopathy in newborns: A randomized control trial.. JPMA. The Journal of the Pakistan Medical Association. 2018. DOI: 10.14444/8817.

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