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DOI 10.1016/s1473-3099(24)00749-7

Медицинская библиотека · The Lancet. Infectious diseases · 2025

Global guideline for the diagnosis and management of candidiasis: an initiative of the ECMM in cooperation with ISHAM and ASM.

Cornely Oliver A, Sprute Rosanne, Bassetti Matteo, Chen Sharon C-A, Groll Andreas H, Kurzai Oliver, Lass-Flörl Cornelia, Ostrosky-Zeichner Luis, Rautemaa-Richardson Riina, Revathi Gunturu, Santolaya Maria E, White P Lewis, Alastruey-Izquierdo Ana, Arendrup Maiken C, Baddley John, Barac Aleksandra, Ben-Ami Ronen, Brink Adrian J, Grothe Jan H, Guinea Jesus, Hagen Ferry, Hochhegger Bruno, Hoenigl Martin, Husain Shahid, Jabeen Kauser, Jensen Henrik E, Kanj Souha S, Koehler Philipp, Lehrnbecher Thomas, Lewis Russell E, Meis Jacques F, Nguyen M Hong, Pana Zoi D, Rath Peter-Michael, Reinhold Ilana, Seidel Danila, Takazono Takahiro, Vinh Donald C, Zhang Sean X, Afeltra Javier, Al-Hatmi Abdullah M S, Arastehfar Amir, Arikan-Akdagli Sevtap, Bongomin Felix, Carlesse Fabianne, Chayakulkeeree Methee, Chai Louis Y A, Chamani-Tabriz Leili, Chiller Tom, Chowdhary Anuradha, Clancy Cornelius J, Colombo Arnaldo L, Cortegiani Andrea, Corzo Leon Dora E, Drgona Lubos, Dudakova Anna, Farooqi Joveria, Gago Sara, Ilkit Macit, Jenks Jeffrey D, Klimko Nikolai, Krause Robert, Kumar Anil, Lagrou Katrien, Lionakis Michail S, Lmimouni Badre E, Mansour Michael K, Meletiadis Joseph, Mellinghoff Sibylle C, Mer Mervyn, Mikulska Malgorzata, Montravers Philippe, Neoh Chin Fen, Ozenci Volkan, Pagano Livio, Pappas Peter, Patterson Thomas F, Puerta-Alcalde Pedro, Rahimli Laman, Rahn Sebastian, Roilides Emmanuel, Rotstein Coleman, Ruegamer Tamara, Sabino Raquel, Salmanton-García Jon, Schwartz Ilan S, Segal Esther, Sidharthan Neeraj, Singhal Tanu, Sinko Janos, Soman Rajeev, Spec Andrej, Steinmann Joerg, Stemler Jannik, Taj-Aldeen Saad J, Talento Alida Fe, Thompson George R, Toebben Christina, Villanueva-Lozano Hiram, Wahyuningsih Retno, Weinbergerová Barbora, Wiederhold Nathan, Willinger Birgit, Woo Patrick C Y, Zhu Li-Ping

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Аннотация

Candida species are the predominant cause of fungal infections in patients treated in hospital, contributing substantially to morbidity and mortality. Candidaemia and other forms of invasive candidiasis primarily affect patients who are immunocompromised or critically ill. In contrast, mucocutaneous forms of candidiasis, such as oral thrush and vulvovaginal candidiasis, can occur in otherwise healthy individuals. Although mucocutaneous candidiasis is generally not life-threatening, it can cause considerable discomfort, recurrent infections, and complications, particularly in patients with underlying conditions such as diabetes or in those taking immunosuppressive therapies. The rise of difficult-to-treat Candida infections is driven by new host factors and antifungal resistance. Pathogens, such as Candida auris (Candidozyma auris) and fluconazole-resistant Candida parapsilosis, pose serious global health risks. Recent taxonomic revisions have reclassified several Candida spp, potentially causing confusion in clinical practice. Current management guidelines are limited in scope, with poor coverage of emerging pathogens and new treatment options. In this Review, we provide updated recommendations for managing Candida infections, with detailed evidence summaries available in the appendix.

Для цитирования: Cornely Oliver A, Sprute Rosanne, Bassetti Matteo, Chen Sharon C-A, Groll Andreas H, Kurzai Oliver, Lass-Flörl Cornelia, Ostrosky-Zeichner Luis, Rautemaa-Richardson Riina, Revathi Gunturu, Santolaya Maria E, White P Lewis, Alastruey-Izquierdo Ana, Arendrup Maiken C, Baddley John, Barac Aleksandra, Ben-Ami Ronen, Brink Adrian J, Grothe Jan H, Guinea Jesus, Hagen Ferry, Hochhegger Bruno, Hoenigl Martin, Husain Shahid, Jabeen Kauser, Jensen Henrik E, Kanj Souha S, Koehler Philipp, Lehrnbecher Thomas, Lewis Russell E, Meis Jacques F, Nguyen M Hong, Pana Zoi D, Rath Peter-Michael, Reinhold Ilana, Seidel Danila, Takazono Takahiro, Vinh Donald C, Zhang Sean X, Afeltra Javier, Al-Hatmi Abdullah M S, Arastehfar Amir, Arikan-Akdagli Sevtap, Bongomin Felix, Carlesse Fabianne, Chayakulkeeree Methee, Chai Louis Y A, Chamani-Tabriz Leili, Chiller Tom, Chowdhary Anuradha, Clancy Cornelius J, Colombo Arnaldo L, Cortegiani Andrea, Corzo Leon Dora E, Drgona Lubos, Dudakova Anna, Farooqi Joveria, Gago Sara, Ilkit Macit, Jenks Jeffrey D, Klimko Nikolai, Krause Robert, Kumar Anil, Lagrou Katrien, Lionakis Michail S, Lmimouni Badre E, Mansour Michael K, Meletiadis Joseph, Mellinghoff Sibylle C, Mer Mervyn, Mikulska Malgorzata, Montravers Philippe, Neoh Chin Fen, Ozenci Volkan, Pagano Livio, Pappas Peter, Patterson Thomas F, Puerta-Alcalde Pedro, Rahimli Laman, Rahn Sebastian, Roilides Emmanuel, Rotstein Coleman, Ruegamer Tamara, Sabino Raquel, Salmanton-García Jon, Schwartz Ilan S, Segal Esther, Sidharthan Neeraj, Singhal Tanu, Sinko Janos, Soman Rajeev, Spec Andrej, Steinmann Joerg, Stemler Jannik, Taj-Aldeen Saad J, Talento Alida Fe, Thompson George R, Toebben Christina, Villanueva-Lozano Hiram, Wahyuningsih Retno, Weinbergerová Barbora, Wiederhold Nathan, Willinger Birgit, Woo Patrick C Y, Zhu Li-Ping. Global guideline for the diagnosis and management of candidiasis: an initiative of the ECMM in cooperation with ISHAM and ASM.. The Lancet. Infectious diseases. 2025. DOI: 10.1016/s1473-3099(24)00749-7.

Предметные рубрики MeSH

HumansAntifungal AgentsCandidiasisCandidaGlobal HealthDrug Resistance, Fungal
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