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DOI 10.1007/bf03325272

Медицинская библиотека · Clinical and experimental rheumatology · 2015

Lack of association of TNFAIP3 and JAK1 with Behçet's disease in the European population.

Ortiz-Fernández Lourdes, García-Lozano José-Raul, Montes-Cano Marco-Antonio, Conde-Jaldón Marta, Ortego-Centeno Norberto, García-Hernández Francisco-Jose, Espinosa Gerard, Graña-Gil Genaro, Sánchez-Bursón Juan, Juliá Maria Rosa, Blanco Ricardo, Barnosi-Marín Ana-Celia, Solans Roser, Fanlo Patricia, Rodríguez Carballeira Monica, Camps Teresa, Castañeda Santos, Martín Javier, González-Escribano Maria-Francisca

СтатьяМногоцентровое исследованиеПоддержка исследования: вне правительства СШАПеревод пока не подготовлен

Аннотация

BACKGROUND

Traumatic cervical spine fractures with dislocation are often caused by high-energy injuries, typically from motor vehicle accidents. Hangman's fracture constitutes 4% to 5% of cervical fractures and is usually accompanied by anteroposterior dislocation and/or neurological deficits. However, lateral vertebral dislocation without neurological symptoms is extremely rare. We present a case of C2 to C3 lateral dislocation with C3 fracture in a patient who only reported neck pain and limited mobility.

METHODS

This study reports a case of a 42-year-old woman who presented with neck pain after a traffic accident. The patient remained fully conscious throughout the incident, and the patient did not experience any loss of consciousness. Preoperative imaging clearly revealed a split fracture of the right C3 body-pedicle junction and the right vertebral plate, along with anterolateral dislocation of the C2 vertebral body. After a closed reduction of the affected segment, an anterior cervical discectomy and fusion (ACDF) was performed to restore segmental stability of the C2 to C3 level.

RESULTS

A satisfied closed reduction was achieved after a fixed cervical traction. An ACDF was performed to successfully restore the segmental stability of the C2 to C3 level without surgical-related complications. The patient reported alleviation of neck pain (visual analog scale score decreased from 7 preoperatively to 2 postoperatively). Postoperative imaging revealed a satisfactory reduction of fracture-dislocation. At a 2-month follow-up after discharge, the patient had returned to work.

CONCLUSION

This case demonstrates the feasibility of ACDF as a standalone approach for treating single-stage cervical fractures with associated lateral dislocation following precise and sustained traction reduction. Compared with posterior or combined approaches, the anterior-only technique offers significant advantages, providing a minimally invasive alternative for the management of complex cervical spine trauma.

CLNICAL RELEVANCE: This case highlights that prompt recognition and surgical stabilization of C3 vertebral body fracture with C2-C3 spondylolisthesis can prevent neurological deterioration and improve functional recovery. It provides practical evidence to support early surgical decision-making in rare but severe cervical spine injuries.

Для цитирования: Ortiz-Fernández Lourdes, García-Lozano José-Raul, Montes-Cano Marco-Antonio, Conde-Jaldón Marta, Ortego-Centeno Norberto, García-Hernández Francisco-Jose, Espinosa Gerard, Graña-Gil Genaro, Sánchez-Bursón Juan, Juliá Maria Rosa, Blanco Ricardo, Barnosi-Marín Ana-Celia, Solans Roser, Fanlo Patricia, Rodríguez Carballeira Monica, Camps Teresa, Castañeda Santos, Martín Javier, González-Escribano Maria-Francisca. Lack of association of TNFAIP3 and JAK1 with Behçet's disease in the European population.. Clinical and experimental rheumatology. 2015. DOI: 10.1007/bf03325272.

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