Familial Mediterranean fever-related spondyloarthropathy.

Familial Mediterranean fever (FMF) is an autosomal recessively-transmitted disease characterised by attacks of fever and serositis. Articular involvement is the second most common manifestation following abdominal pain. Patients with FMF are considered to have an increased risk of sacroiliitis, while the association of such abnormalities with FMF has not been accepted uniformly. We report two cases of FMF with accompanying seronegative spondyloarthropathy, a 18-year-old boy and a 29-year-old man, and review the literature for FMF-related seronegative spondyloarthropathy.