Antiglomerular Basement Membrane (Anti-GBM) Glomerulonephritis in the Context of Genitourinary Tuberculosis: A Case Report.

Antiglomerular basement membrane (anti-GBM) glomerulonephritis (GN) has been reported to be associated with tuberculosis (TB), but anti-GBM GN in the context of genitourinary TB is exceptionally rare. We report a case of anti-GBM GN with concurrent genitourinary TB. The patient underwent plasma exchange and was treated with high-dose prednisolone following a 3-day course of intravenous methylprednisolone. Oral cyclophosphamide (125 mg once daily) was also prescribed. After 14 cycles of plasma exchange, the anti-GBM antibody titer decreased. However, the patient developed pulmonary hemorrhage requiring intubation and remained dialysis dependent despite therapy.