Standardization of infection [18F]FDG-PET/CT imaging protocols and reporting criteria.

[18F]FDG-PET/CT (infection PET) has emerged as a key modality in the evaluation and management of patients with suspected or proven infection. Despite several recommendations addressing general preparation, acquisition, interpretation and reporting, infection PET/CT remains insufficiently standardized across indications and centers. This review provides a comprehensive overview of general and indication-specific aspects of infection PET and proposes clinically applicable suggestions to harmonize protocols, maximize the diagnostic performance and its contribution to patient management.