International journal of STD & AIDS · 2025
Acute rhabdomyolysis in a woman living with HIV - antiretroviral treatment is not always to blame.
СтатьяКлинический случайНазвание и аннотация: Перевод в очереди
Обработка статьи · этапы, ошибки и управление
Загрузка состояния…
Ошибки и ограничения
История · было → стало
Состояние обновляется каждые 5 секунд, пока блок открыт. Процент показывается только там, где известен объём работы. Пауза останавливает продолжение этапа; текущий запрос к источнику может завершиться.
Probst Léa, Dubois Maxime, Risser Clémence, Bernard-Henry Claudine, Groza Monica, Rey David, Ursenbach Axel
Аннотация
We report a 49-year-old woman living with HIV who stopped her antiretroviral treatment for several weeks. One month after resuming treatment with dolutegravir and lamivudine (Dovato®), she presented with myalgia, physical weakness and rhabdomyolysis. As we suspected a drug-related cause, Dovato® was changed for tenofovir disoproxil fumarate, lamivudine and doravirine (Delstrigo®) without improvement. Second line assessment led to a diagnosis of dermatomyositis, with presence of anti-Mi-2 antibodies, typical MRI findings and pathological analysis of muscle biopsy. The outcome was favorable after treatment with corticosteroids followed by methotrexate. Dovato® was subsequently re-prescribed without recurrence of symptoms or rhabdomyolysis.