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DOI 10.18632/oncotarget.13745

Медицинская библиотека · Oncotarget · 2017

The association between serum uric acid and glaucoma severity in primary angle closure glaucoma: a retrospective case-control study.

Di Matteo Andrea, Filippucci Emilio, Cipolletta Edoardo, Martire Victoria, Jesus Diogo, Musca Alice, Corradini Davide, Isidori Martina, Salaffi Fausto, Grassi Walter

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Аннотация

OBJECTIVES

To explore the prevalence of the ultrasound (US) findings of enthesitis in a group of healthy subjects.

METHODS

US assessments of quadriceps, patellar and Achilles tendons, and plantar fascia entheses were performed by a rheumatologist on 82 healthy volunteers focusing on the US findings indicative of "active" inflammation according to the Outcome Measures in Rheumatology (OMERACT) definitions.

RESULTS

Eight hundred and twenty entheses were evaluated in 82 healthy subjects. One or more US findings of "active" inflammation were found in at least one enthesis in 30 out of 82 subjects (34.1%), in 69 out of 820 entheses (8.4%). Entheseal thickening, hypoechogenicity and PD signal were respectively found in at least one enthesis in 23 (28.0%), 11 (13.4%) and 8 (9.8%) out of 82 subjects. Among the 69 entheses showing US features of "active" inflammation, entheseal thickening, hypoechogenicity and PD signal were found as isolated in 61 entheses and in combination in the remaining 8 (entheseal thickening and hypoechogenicity).

CONCLUSIONS

Our results show a relatively high prevalence of US findings of "active" inflammation at the lower limb entheses in a group of healthy subjects, thus questioning the discriminant power of the OMERACT definitions for the diagnosis of "active" enthesitis. A combination of grey-scale and PD findings at a specific threshold to be defined could improve both the reliability and clinical usefulness of US.

Для цитирования: Di Matteo Andrea, Filippucci Emilio, Cipolletta Edoardo, Martire Victoria, Jesus Diogo, Musca Alice, Corradini Davide, Isidori Martina, Salaffi Fausto, Grassi Walter. The association between serum uric acid and glaucoma severity in primary angle closure glaucoma: a retrospective case-control study.. Oncotarget. 2017. DOI: 10.18632/oncotarget.13745.

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