Annals of allergy, asthma & immunology : official publication of the American College of Allergy, Asthma, & Immunology · 2003
A case report of wegener granulomatosis treated only with corticosteroids for 30 years.
Клинический случайСтатьяНазвание и аннотация: Перевод в очереди
Обработка статьи · этапы, ошибки и управление
Загрузка состояния…
Ошибки и ограничения
История · было → стало
Состояние обновляется каждые 5 секунд, пока блок открыт. Процент показывается только там, где известен объём работы. Пауза останавливает продолжение этапа; текущий запрос к источнику может завершиться.
PausJenssen Elizabeth S, Cockcroft Donald W
Аннотация
BACKGROUND: Wegener granulomatosis is a systemic vasculitis classically described as involving the upper and lower respiratory tracts together with glomerulonephritis. Its poor prognosis was marginally improved with the use of corticosteroids, and long-term remission was not achieved until the introduction of cytotoxic agents. Generalized or systemic Wegener granulomatosis has a worse prognosis than those limited to the respiratory tracts.
OBJECTIVE: To report the case of an individual who we suspect has a 30-year history of Wegener granulomatosis treated only with prednisone.
METHODS: A literature search was performed with PubMed using the keywords Wegener granulomatosis, survival, prognosis, and treatment.
RESULTS: Our patient is alive 32 years after her initial symptoms of vasculitis. She has been taking daily prednisone only for the majority of this time. Our clinical diagnosis of Wegener granulomatosis is based on the history and very high antineutrophil cytoplasmic antibody with the cytoplasmic pattern.
CONCLUSIONS: There may be variants of generalized Wegener granulomatosis that survive with less aggressive treatment.
OBJECTIVE: To report the case of an individual who we suspect has a 30-year history of Wegener granulomatosis treated only with prednisone.
METHODS: A literature search was performed with PubMed using the keywords Wegener granulomatosis, survival, prognosis, and treatment.
RESULTS: Our patient is alive 32 years after her initial symptoms of vasculitis. She has been taking daily prednisone only for the majority of this time. Our clinical diagnosis of Wegener granulomatosis is based on the history and very high antineutrophil cytoplasmic antibody with the cytoplasmic pattern.
CONCLUSIONS: There may be variants of generalized Wegener granulomatosis that survive with less aggressive treatment.