The journal of prevention of Alzheimer's disease · 2026
Sex differences in subjective cognition among middle-aged and older Hispanic/Latino adults: Findings from the HCHS/SOL and SOL-INCA.
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Stickel Ariana M, Tarraf Wassim, Kuwayama Sayaka, Xie Ammie, Membreno Rachel, Costa Carolina L, Araujo Menendez Carlos E E, Zlatar Zvinka Z, Perreira Krista M, Zhou Haibo, Daviglus Martha, Pirzada Amber, Filigrana Paola, Levin Bonnie E, Gallo Linda C, González Hector M, Banks Sarah J
Аннотация
INTRODUCTION: Sex differences in subjective cognitive decline (SCD) exist, yet the extent to which these differences generalize to underrepresented groups is unknown. Therefore, we investigated relationships between sex and SCD among Hispanic/Latino adults.
METHOD: Participants were 5985 Hispanic/Latino adults from the Study of Latinos - Investigation of Neurocognitive Aging. We performed survey-adjusted linear regressions to test the associations between sex (male/female) with SCD and modifications by cardiovascular disease (CVD) risk, social and language acculturation. SCD was measured using the Everyday Cognition 12-item questionnaire, including executive functioning, memory, language, and visuospatial domains.
RESULT: Overall, females reported more SCD in language and visuospatial domains. This was less pronounced for 1) language SCD at lower levels of CVD risk, and 2) visuospatial SCD with higher language acculturation.
DISCUSSION: Hispanic/Latina females self-reported more cognitive decline than males, but these differences were less pronounced in the context of lower CVD risk and higher language acculturation.
METHOD: Participants were 5985 Hispanic/Latino adults from the Study of Latinos - Investigation of Neurocognitive Aging. We performed survey-adjusted linear regressions to test the associations between sex (male/female) with SCD and modifications by cardiovascular disease (CVD) risk, social and language acculturation. SCD was measured using the Everyday Cognition 12-item questionnaire, including executive functioning, memory, language, and visuospatial domains.
RESULT: Overall, females reported more SCD in language and visuospatial domains. This was less pronounced for 1) language SCD at lower levels of CVD risk, and 2) visuospatial SCD with higher language acculturation.
DISCUSSION: Hispanic/Latina females self-reported more cognitive decline than males, but these differences were less pronounced in the context of lower CVD risk and higher language acculturation.