American journal of ophthalmology · 1999
Antithymocyte globulin treatment of orbital Wegener granulomatosis: a follow-up study.
Клинический случайСтатьяНазвание и аннотация: Перевод в очереди
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Kool J, de Keizer R J, Siegert C E
Аннотация
PURPOSE: To describe the follow-up of patients with orbital Wegener granulomatosis after antithymocyte globulin treatment.
METHODS: Patients with ocular/orbital Wegener granulomatosis refractory to standard treatment were selected for immunotherapy with rabbit antithymocyte globulin intravenously. The specific ocular/orbital symptoms were monitored in patients with a vision-threatening form of Wegener granulomatosis or a life-threatening form with ocular symptoms.
RESULTS: One patient had a complete remission, two patients had remissions but still needed additional treatment, and one patient remained refractory.
CONCLUSIONS: In selected patients, antithymocyte globulin immunotherapy may present an alternative when vision or life is threatened by orbital Wegener granulomatosis.
METHODS: Patients with ocular/orbital Wegener granulomatosis refractory to standard treatment were selected for immunotherapy with rabbit antithymocyte globulin intravenously. The specific ocular/orbital symptoms were monitored in patients with a vision-threatening form of Wegener granulomatosis or a life-threatening form with ocular symptoms.
RESULTS: One patient had a complete remission, two patients had remissions but still needed additional treatment, and one patient remained refractory.
CONCLUSIONS: In selected patients, antithymocyte globulin immunotherapy may present an alternative when vision or life is threatened by orbital Wegener granulomatosis.