Imaging Features of Neurosarcoidosis in FDG PET/CT.

Sarcoidosis is a systemic noncaseating granulomatous immune-mediated disease with multiorgan involvement. Neurosarcoidosis was historically reported to occur in 5%-10% of all patients with sarcoidosis. Neurosarcoidosis can present with a myriad of clinical symptoms, including cranial neuropathy, myelopathy, and parenchymal involvement. Conventional imaging is often nonspecific and central nervous system biopsy to confirm the diagnosis is infrequently performed. Fluorodeoxyglucose positron emission tomography/computed tomography (FDG PET/CT) is a useful modality in the evaluation of neurosarcoidosis, for assessing systemic involvement and identifying biopsiable site. We present the case of neurosarcoidosis with FDG PET/CT detected rare cranial and spinal radiculopathy lesions apart from other systemic findings.