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DOI 10.1016/j.wneu.2020.12.048

Медицинская библиотека · World neurosurgery · 2020

Degenerative Lumbar Stenosis Surgery: Predictive Factors of Clinical Outcome-Experience with 1001 Patients.

Aimar Enrico, Iess Guglielmo, Gaetani Paolo, Galbiati Tommaso Francesco, Isidori Alessandra, Lavanga Vito, Longhitano Federico, Menghetti Claudia, Messina Alberto Luca, Zekaj Edvin, Broggi Giovanni

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Аннотация

BACKGROUND

Degenerative lumbar spinal stenosis (DLSS) carries a high risk of morbidity and represents a financial burden to society. A late diagnosis can lead to severe disability. Although lumbar decompressive surgery has been widely used worldwide, the proper preoperative factors to define the ideal candidates for decompression are missing.

METHODS

A total of 1001 patients who had undergone decompressive surgery from 2012 to 2019 for DLSS were screened for the presence of 9 clinical and radiological parameters. For all cases, the differences between the baseline and postoperative Oswestry disability index were calculated and the results categorized as 5 different classes (ranging from very poor outcomes to excellent outcomes) according to the specific scores. Generalized ordinal logistic regression was then used to analyze the significance of the 9 parameters (coded as dummy variables) in predicting the outcome as measured by Oswestry disability index improvement after surgery.

RESULTS

Of the 9 parameters, 8 were found to be significant predictors. The radiological grade of compression was the strongest, followed by polyneuropathy, obesity, symptom duration, gait autonomy, radicular deficits, American Society of Anesthesiologists score, and level of surgery. In contrast, previous back surgery was not predictive of the outcome.

CONCLUSIONS

Our findings have indicated that the ideal candidate for surgery will have the following preoperative characteristics: Schizas grade D, no signs of peripheral polyneuropathy, body mass index <30 kg/m2, symptom duration of <2 years, gait autonomy <100 m, no radicular deficits, 1 level of stenosis, and an American Society of Anesthesiologists score of 1, 2, or 3.

Для цитирования: Aimar Enrico, Iess Guglielmo, Gaetani Paolo, Galbiati Tommaso Francesco, Isidori Alessandra, Lavanga Vito, Longhitano Federico, Menghetti Claudia, Messina Alberto Luca, Zekaj Edvin, Broggi Giovanni. Degenerative Lumbar Stenosis Surgery: Predictive Factors of Clinical Outcome-Experience with 1001 Patients.. World neurosurgery. 2020. DOI: 10.1016/j.wneu.2020.12.048.

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