Child's nervous system : ChNS : official journal of the International Society for Pediatric Neurosurgery · 2015
Risk factors for surgical site infection following pediatric spinal deformity surgery: a systematic review and meta-analysis.
СтатьяМетаанализСистематический обзорНазвание и аннотация: Перевод в очереди
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Meng Fei, Cao Junming, Meng Xianzhong
Аннотация
PURPOSE: This study was conducted to identify risk factors for postoperative infection after pediatric spinal deformity surgery.
METHODS: A systematic electronic literature search from inception to November 2014 was performed in the following databases: Pubmed, Embase, and Cochrane library databases. Pooled odds ratios (ORs) or standardized mean differences (SMDs) with 95 % confidence intervals (CIs) were calculated using random or fixed effects model. Newcastle-Ottawa scale was used to evaluate the methodological quality, and Stata 11.0 was used to analyze data.
RESULTS: The main factors associated with infection after spinal surgery were idiopathic scoliosis (OR, 0.303; 95 % CI, 0.202-0.453), neuromuscular scoliosis (OR, 2.269; 95 % CI, 1.576-3.267), ambulatory status (OR, 0.241; 95 % CI, 0.078-0.747), previous spinal surgery (OR, 4.564; 95 % CI, 1.892-11.009), sacral vertebrae fused (OR, 2.717; 95 % CI, 1.836-4.020), and allograft (OR, 8.498; 95 % CI, 4.030-17.917). There was no sufficient evidence to reveal that male gender, age, body mass index, preoperative curve, preoperative urinary tract infection, combined anterior-posterior approach, estimated blood loss, and operating room time could lead to infection after spinal surgery.
CONCLUSIONS: We identified some risk factors which could be used to prevent the onset of surgical site infection in pediatric spinal deformity surgery. However, the results of this meta-analysis should be interpreted with caution because of the heterogeneity among the studies.
METHODS: A systematic electronic literature search from inception to November 2014 was performed in the following databases: Pubmed, Embase, and Cochrane library databases. Pooled odds ratios (ORs) or standardized mean differences (SMDs) with 95 % confidence intervals (CIs) were calculated using random or fixed effects model. Newcastle-Ottawa scale was used to evaluate the methodological quality, and Stata 11.0 was used to analyze data.
RESULTS: The main factors associated with infection after spinal surgery were idiopathic scoliosis (OR, 0.303; 95 % CI, 0.202-0.453), neuromuscular scoliosis (OR, 2.269; 95 % CI, 1.576-3.267), ambulatory status (OR, 0.241; 95 % CI, 0.078-0.747), previous spinal surgery (OR, 4.564; 95 % CI, 1.892-11.009), sacral vertebrae fused (OR, 2.717; 95 % CI, 1.836-4.020), and allograft (OR, 8.498; 95 % CI, 4.030-17.917). There was no sufficient evidence to reveal that male gender, age, body mass index, preoperative curve, preoperative urinary tract infection, combined anterior-posterior approach, estimated blood loss, and operating room time could lead to infection after spinal surgery.
CONCLUSIONS: We identified some risk factors which could be used to prevent the onset of surgical site infection in pediatric spinal deformity surgery. However, the results of this meta-analysis should be interpreted with caution because of the heterogeneity among the studies.