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Войти в исследования Dakar medical · 2005
[Clinical and evolutionary aspects of polymyosite in internal medicine].
Аннотация на английскомСтатьяНазвание и аннотация: Перевод в очереди
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Ndongo S, Pouye A, Ka M M, Leye A, Ndiaye A D, Diop T M
Аннотация
INTRODUCTION: Polymyositis is a chronic inflammatory disease possibly responsable of various systemic manifestations.
PATIENTS AND METHODS: Reported is a retrospective done on polymyositis i n internal medecine department in patients from march 1997 to april 2002.
RESULTS: Eleven cases were collected from a total of 6739 admissions giving a prevalence of 0.16%. Sex ratio was 1.2(F/H) with a mean age of 33 years. The most frequent clinical presentation was the muscle signs. It was dominated by the functionnal disability (90.9%), myalgia (81.8%) and dysphagia (36.3%). Systemic manifestations of polymyositis interested articulary, bronchopulmonary, cardiac and neurological areas. Association of polymyositis and other sytemic disease has been found in one patient, who presented also a rhumatoid arthritis. First step treatment was corticotherapy for all patients. Immunosuppressor with azathioprine have been introduced in 2 patients who presented an associated interstitial nulmonary disease. On this treatment we observed 4 cases of total remission, 3 cases of partial remission, 2 death occured and 2 patients have been lost from clinical follow up.
CONCLUSION: The long term follow of these chronic disease is a major problem in developping countries. Most of the patients live far from hospital centers and don't have possibility to do complementary exams so as to buy regulary the drugs.
PATIENTS AND METHODS: Reported is a retrospective done on polymyositis i n internal medecine department in patients from march 1997 to april 2002.
RESULTS: Eleven cases were collected from a total of 6739 admissions giving a prevalence of 0.16%. Sex ratio was 1.2(F/H) with a mean age of 33 years. The most frequent clinical presentation was the muscle signs. It was dominated by the functionnal disability (90.9%), myalgia (81.8%) and dysphagia (36.3%). Systemic manifestations of polymyositis interested articulary, bronchopulmonary, cardiac and neurological areas. Association of polymyositis and other sytemic disease has been found in one patient, who presented also a rhumatoid arthritis. First step treatment was corticotherapy for all patients. Immunosuppressor with azathioprine have been introduced in 2 patients who presented an associated interstitial nulmonary disease. On this treatment we observed 4 cases of total remission, 3 cases of partial remission, 2 death occured and 2 patients have been lost from clinical follow up.
CONCLUSION: The long term follow of these chronic disease is a major problem in developping countries. Most of the patients live far from hospital centers and don't have possibility to do complementary exams so as to buy regulary the drugs.